Structure-Based Design of Substituted Piperidines as a New Class of Highly Efficacious Oral Direct Renin Inhibitors
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چکیده
منابع مشابه
SbCl3 as an Efficient Catalyst for the One-pot Synthesis of Highly Substituted Piperidines
Highly substituted piperidines were synthesized via the condensation of aromatic aldehydes and aromatic amines with β-ketoesters in the presence of antimony(III) chloride at ambient condition. This reaction has any advantages such as easy work-up, clean procedure, and good yields.
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ژورنال
عنوان ژورنال: ACS Medicinal Chemistry Letters
سال: 2014
ISSN: 1948-5875,1948-5875
DOI: 10.1021/ml500137b